[1]董金铧,胡慧景,邓炳耀,等.医用多功能水凝胶纤维基非织造布的制备与性能[J].服装学报,2025,10(05):384-388.
 DONG Jinhua,HU Huijing,DENG Bingyao,et al.Preparation and Performance of Medical Multifunctional Hydrogel Fiber Based Nonwoven Fabrics[J].Journal of Clothing Research,2025,10(05):384-388.
点击复制

医用多功能水凝胶纤维基非织造布的制备与性能()

《服装学报》[ISSN:2096-1928/CN:32-1864/TS]

卷:
第10卷
期数:
2025年05期
页码:
384-388
栏目:
服装材料
出版日期:
2025-11-01

文章信息/Info

Title:
Preparation and Performance of Medical Multifunctional Hydrogel Fiber Based Nonwoven Fabrics
作者:
董金铧;  胡慧景;  邓炳耀;  李大伟*
江南大学 纺织科学与工程学院,江苏 无锡 214122
Author(s):
DONG Jinhua;  HU Huijing;  DENG Bingyao;  LI Dawei*
College of Textile Science and Engineering, Jiangnan University, Wuxi 214122, China
分类号:
TS 171
文献标志码:
A
摘要:
以天然多糖羧甲基壳聚糖与羧甲基纤维素钠为纺丝原料,槲皮素作为功能因子,结合水动力牵伸纺丝技术与湿法成网制备柔软亲水、抗氧化、快速止血的多功能水凝胶纤维基非织造布(HFN),探讨HFN的微观形貌、水蒸气透过率、抗氧化活性、体外止血性能。研究得出,HFN的水蒸气透过率为2 975.91 g/(m2·d),且具有良好的超亲水性,能够在0.05 s内完全吸收10 μL水滴; HFN对1,1-二苯基-2-苦基肼自由基的清除率为82.63%,表明其具有优异的抗氧化活性; 该材料具有良好的血液相容性,体外凝血指数为30.07%,血液凝固时间为7.92 s,明显优于棉纱布对照组。结果表明,HFN具有优异的抗氧化活性与快速止血性能。该研究为医用服装面料的开发提供了新的思路。
Abstract:
Utilizing natural polysaccharides carboxymethyl chitosan and sodium carboxymethyl cellulose as spinning raw materials, and quercetin as the functional factor, multifunctional hydrogel fiber-based nonwoven fabric(HFN)with softness, hydrophilicity, antioxidant activity, and rapid hemostatic performance was fabricated by combining hydrodynamic drafting spinning platform with wet-laid web formation. The study investigated the microscopic morphology, water vapor transmission rate, antioxidant activity, and in vitro hemostatic performance of HFN. The results showed that the water vapor transmission rate of HFN was 2 975.91 g/(m2·d), and it exhibited excellent superhydrophilicity, capable of completely absorbing a 10 μL water droplet within 0.05 s. The scavenging rate of HFN against 1,1-diphenyl-2-picrylhydrazyl free radicals reached 82.63%, demonstrating outstanding antioxidant activity. The material also displayed good blood compatibility, with an in vitro blood clotting index of 30.07% and a blood coagulation time of 7.92 s, which were significantly superior to those of the cotton gauze control group. The results indicate that HFN possesses excellent antioxidant activity and rapid hemostatic performance. This study provides new research insights for the development of medical clothing fabrics.

参考文献/References:

[1] WANG K, WANG J H, LI L, et al. Synthesis of a novel anti-freezing, non-drying antibacterial hydrogel dressing by one-pot method[J]. Chemical Engineering Journal, 2019, 372: 216-225.
[2] YU R, YANG Y T, HE J H, et al. Novel supramolecular self-healing silk fibroin-based hydrogel via host-guest interaction as wound dressing to enhance wound healing[J]. Chemical Enginee-ring Journal, 2021, 417: 128278.
[3] WANG W Z, JIA B, XU H R, et al. Multiple bonds crosslinked antibacterial, conductive and antioxidant hydrogel adhesives with high stretchability and rapid self-healing for MRSA infected motion skin wound healing[J]. Chemical Engineering Journal, 2023, 468: 143362.
[4] LIU G H, WANG L, HE Y, et al. Polydopamine nanosheets doped injectable hydrogel with nitric oxide release and photothe-rmal effects for bacterial ablation and wound healing[J]. Advanced Healthcare Materials, 2021, 10(23): 2101476.
[5] LIU P, JIN K, WONG W, et al. Ionic liquid functionalized non-releasing antibacterial hydrogel dressing coupled with electrical stimulation for the promotion of diabetic wound healing[J]. Chemical Engineering Journal, 2021, 415: 129025.
[6] CHENG W, WANG M, CHEN M, et al. Injectable antibacterial antiinflammatory molecular hybrid hydrogel dressing for rapid MDRB-infected wound repair and therapy[J]. Chemical Enginee-ring Journal, 2021, 409: 128140.
[7] LI Y, FU R Z, DUAN Z G, et al. Artificial nonenzymatic antioxidant MXene nanosheet-anchored injectable hydrogel as a mild photothermal-controlled oxygen release platform for diabetic wound healing[J]. ACS Nano, 2022, 16(5): 7486-7502.
[8] LI Z Y, ZHANG X J, GAO Y M, et al. Photo-responsive hydrogel for contactless dressing change to attenuate secondary damage and promote diabetic wound healing[J]. Advanced Healthcare Materials, 2023, 12(17): 2202770.
[9] 苏宪浩, 薛浩, 宋晓璐. 智能水凝胶敷料促进慢性伤口愈合的研究进展[J]. 化工新型材料, 2023, 51(增2): 150-154.
SU Xianhao, XUE Hao, SONG Xiaolu. Research progress of intelligent hydrogel dressing in promoting chronic wound healing[J]. New Chemical Materials, 2023, 51(Sup.2): 150-154.
[10] ALIZADEHGIASHI M, NEMR C R, CHEKINI M, et al. Multifunctional 3D-printed wound dressings[J]. ACS Nano, 2021, 15(7): 12375-12387.
[11] ZHAO P, ZHANG Y, CHEN X A, et al. Versatile hydrogel dres-sing with skin adaptiveness and mild photothermal antibacterial activity for methicillin-resistant staphylococcus aureus-infected dynamic wound healing[J]. Advanced Science, 2023, 10(11): 2206585.
[12] JIANG S H, DENG J J, JIN Y H, et al. Breathable, antifreezing, mechanically skin-like hydrogel textile wound dressings with dual antibacterial mechanisms[J]. Bioactive Materials, 2023, 21: 313-323.
[13] 王亚茹, 袁满, 张丽, 等. 槲皮素抗氧化作用及相关机制研究进展[J]. 营养学报, 2022, 44(2): 204-208.
WANG Yaru, YUAN Man, ZHANG Li, et al. Research progress on antioxidant actions and related mechanisms of quercetin[J]. Acta Nutrimenta Sinica, 2022, 44(2): 204-208.(in Chinese)
[14] 国家食品药品监督管理局. 接触性创面敷料试验方法 第2部分:透气膜敷料水蒸气透过率: YY/T 0471.2—2004[S]. 北京:中国标准出版社, 2004.
[15] LI X Z, YANG X X, WANG Z C, et al. Antibacterial, antioxidant and biocompatible nanosized quercetin-PVA xerogel films for wound dressing[J]. Colloids and Surfaces B: Biointerfaces, 2022, 209: 112175.
[16] 邢美毅, 王欣悦, 王璐, 等. PVA/PAAm水凝胶人工血管材料及其血液相容性[J]. 东华大学学报(自然科学版), 2021, 47(1): 14-20.
XING Meiyi, WANG Xinyue, WANG Lu, et al. PVA/PAAm hydrogel vascular graft materials and the hemocompatibility[J]. Journal of Donghua University(Natural Science), 2021, 47(1): 14-20.(in Chinese)
[17] 罗爽, 巫瑛, 李慧敏, 等. 壳聚糖/海藻酸钙止血海绵的制备与性能[J]. 现代纺织技术, 2025, 33(3): 8-15.
LUO Shuang, WU Ying, LI Huimin, et al. Preparation and properties of a chitosan/calcium alginate hemostatic sponge[J]. Advanced Textile Technology, 2025, 33(3): 8-15.(in Chinese)
[18] 管彤, 张锋. 生物活性丝素蛋白敷料在创面修复中的研究进展[J]. 丝绸, 2023, 60(2): 35-41.
GUAN Tong, ZHANG Feng. Bioactive silk protein dressings in wound repair[J]. Journal of Silk, 2023, 60(2): 35-41.(in Chinese)
[19] 马丕波, 梅德轩. 生物医用纺织材料研究应用与进展[J]. 服装学报, 2022, 7(3):189-195.
MA Pibo, MEI Dexuan. Research application and progress of biomedical textile materials[J]. Journal of Clothing Research, 2022, 7(3): 189-195.(in Chinese)
[20] ZHOU L Z, CAI L, RUAN H J, et al. Electrospun chitosan oligosaccharide/polycaprolactone nanofibers loaded with wound-healing compounds of Rutin and Quercetin as antibacterial dressings[J]. International Journal of Biological Macromolecules, 2021, 183: 1145-1154.
[21] YU X S, CHENG C, PENG X, et al. A self-healing and injectable oxidized quaternized guar gum/carboxymethyl chitosan hydrogel with efficient hemostatic and antibacterial properties for wound dressing[J]. Colloids and Surfaces B: Biointerfaces, 2022, 209: 112207.
[22] HUANG W J, CHENG S, WANG X L, et al. Noncompressible hemostasis and bone regeneration induced by an absorbable bioadhesive self-healing hydrogel[J]. Advanced Functional Materials, 2021, 31(22): 2009189.

更新日期/Last Update: 2025-10-30